Web apps and databases developed and maintained by the Bioinformatics Unit and collaborating groups at IMBB-FORTH.
A web app for designing double-stranded RNA (dsRNA) sequences with a focus on safety for non-target organisms (NTOs). Candidate sequences are screened against NTO databases to flag potential cross-reactivity before synthesis, reducing the risk of unintended effects in RNAi-based applications.
Developed at IMBB-FORTH as part of ongoing work on RNAi pest management and vector biology.
A companion tool to the dsRNA Analyzer. Where the Analyzer checks safety against non-target organisms, this app screens candidate dsRNA sequences for specificity within the target organism — ensuring the sequence hits the intended gene and avoids off-target effects within the same genome.
Developed and hosted by the Bioinformatics Unit at IMBB-FORTH.
A curated resource for arthropod cytochrome P450 (CYP) enzyme nomenclature and sequences. Covers insects, ticks, and other arthropods with standardized naming conventions, sequence alignments, phylogenetic classifications, and links to associated literature.
Developed and maintained by Drs. Jason Charamis (IMBB-FORTH) and Rene Feyereisen (Ghent University) and hosted at IMBB-FORTH.
Please cite: Charamis, J., Dermauw, W., Van Leeuwen, T., Vontas, J., Feyereisen, R., 2025. The Arthropod P450 Enchiridion: An integrated web resource for research on P450s, Insect Biochemistry and Molecular Biology, 183: 104377.
Additional tools and databases are under development. To suggest a collaboration or request a custom tool for your research, get in touch.
We develop bespoke scripts, web apps, and databases for research groups at IMBB and the University of Crete.
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