About
Christos Andronis currently leads the Bioinformatics Unit at IMBB-FORTH. Before joining IMBB, Christos has held similar positions at Deus ex Machina (ekmechanes.com), Biovista and Protein Pathways, Inc. Apart from coordinating projects that involve Bioinformatics omics data analyses, Christos has been leading biomedical data integration and harmonization projects using Ontological frameworks and controlled vocabularies following FAIR principles. In his past positions, Dr. Andronis has also been heavily involved in the systematic drug repurposing and drug adverse event predictions fields. Dr. Andronis has a long-standing interest in transforming experimental and textual data into knowledge useful to biomedical research.
Selected Publications
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Building an Adverse Outcome Pathway network for COVID-19.
Nymark P, Clerbaux LA, Amorim MJ, Andronis C, et al. Front Syst Biol. 2024 Jun 6;4:1384481.
doi: 10.3389/fsysb.2024.1384481 · PMID: 40206642
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Broadening the Nicotiana benthamiana research toolbox through the generation of dicer-like mutants using CRISPR/Cas9 approaches.
Bardani E, Katsarou K, Mitta E, Andronis C, et al. Plant Sci. 2025 Jul;356:112490.
doi: 10.1016/j.plantsci.2025.112490 · PMID: 40174865
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dsRNAEngineer: a web-based tool of comprehensive dsRNA design for pest control.
Chen Y, Shi Y, Wang Z, An X, Wei S, Andronis C, Vontas J, Wang JJ, Niu J. Trends Biotechnol. 2025 Apr;43(4):969–983.
doi: 10.1016/j.tibtech.2025.01.002 · PMID: 39924355
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Stress-related transcriptomic changes associated with GFP transgene expression and active transgene silencing in plants.
Kallemi P, Verret F, Andronis C, Ioannidis N, Glampedakis N, Kotzabasis K, Kalantidis K. Sci Rep. 2024 Jun 10;14(1):13314.
doi: 10.1038/s41598-024-63527-5 · PMID: 38858413
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PSTVd infection in Nicotiana benthamiana plants has a minor yet detectable effect on CG methylation.
Tselika M, Belmezos N, Kallemi P, Andronis C, et al. Front Plant Sci. 2023 Oct 31;14:1258023.
doi: 10.3389/fpls.2023.1258023 · PMID: 38023875
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GABAA receptor-mediated seizure liabilities: a mixed-methods screening approach.
Bampali K, Koniuszewski F, Vogel FD, Fabjan J, Andronis C, et al. Cell Biol Toxicol. 2023 Dec;39(6):2793–2819.
doi: 10.1007/s10565-023-09803-y · PMID: 37093397
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Literature mining, ontologies and information visualization for drug repurposing.
Andronis C, Sharma A, Virvilis V, Deftereos S, Persidis A. Brief Bioinform. 2011 Jul;12(4):357–68.
doi: 10.1093/bib/bbr005 · PMID: 21712342
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Drug repurposing and adverse event prediction using high-throughput literature analysis.
Deftereos SN, Andronis C, Friedla EJ, Persidis A, Persidis A. Wiley Interdiscip Rev Syst Biol Med. 2011 May–Jun;3(3):323–34.
doi: 10.1002/wsbm.147 · PMID: 21416632
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CIRCADIAN CLOCK ASSOCIATED1 and LATE ELONGATED HYPOCOTYL function synergistically in the circadian clock of Arabidopsis.
Lu SX, Knowles SM, Andronis C, Ong MS, Tobin EM. Plant Physiol. 2009 Jun;150(2):834–43.
doi: 10.1104/pp.108.133272 · PMID: 19218364
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The clock protein CCA1 and the bZIP transcription factor HY5 physically interact to regulate gene expression in Arabidopsis.
Andronis C, Barak S, Knowles SM, Sugano S, Tobin EM. Mol Plant. 2008 Jan;1(1):58–67.
doi: 10.1093/mp/ssm005 · PMID: 20031914
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Novel biological networks modulated by complement.
Mastellos D, Andronis C, Persidis A, Lambris JD. Clin Immunol. 2005 Jun;115(3):225–35.
doi: 10.1016/j.clim.2005.03.012 · PMID: 15893689
